Development of a novel microdevice for sorptive extraction under a green analytical chemistry approach: Application for bioanalytical determination of Ibuprofen

This study proposes a novel device called micro polymeric magnetized bar adsorptive extraction (µ-PMBAE), as an and enrichment technique for trace analysis in aqueous samples. These micro-bar absorbent devices were prepared using easily accessible low-cost materials, incorporating different sorbent materials into polymer introducing small piece of neodymium magnet. Several stability tests applied to determine their robustness, stability, weight variation; finally, ibuprofen concentration urine samples was determined, demonstrating the applicability under green analytical chemistry approach. The µ-PMBAE showed remarkable advantages since sorbents can be added hot melt glue. tunes interaction with analytes become more specific extraction. Likewise, magnetic ability makes it possible carry out without extra stir bar, matching its performance traditional commercially based on polydimethylsiloxane phase. proposed method demonstrated excellent concerning high recovery percentages, adequate coefficients variation, low detection limits.